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實驗室

10:30-11:30, Wednesday, April 24, 2019


Speaker: Yishi Jin, Ph.D.

Professor and Chair

Section of Neurobiology, Division of Biological Sciences

University of California, San Diego

Topic: Dissecting MAP kinase signaling in neuronal stress and organism development

Host:  Mengqiu Dong, Ph.D.

Abstract

Using single axon injury assay in C. elegans, we have systematically screened the function of >1200 selected C. elegans genes and identified numerous axon regeneration pathways. Among them, we have elucidated signaling pathways for the DLK-1 MAP kinase.  In parallel studies, we have characterized a different MAP kinase cascade that is broadly implicated in innate immunity and organism development. In this talk, I will describe the findings and strategies to understand the context specificity of MAP kinase mediated signal transduction mechanisms.